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The small G-proteins Rac1 and Cdc42 are essential for myoblast fusion in the mouse
Rac1 and Cdc42 are small G-proteins that regulate actin dynamics and affect plasma membrane protrusion and vesicle traffic. We used conditional mutagenesis in mice to demonstrate that Rac1 and Cdc42 are essential for myoblast fusion in vivo and in vitro. The deficit in fusion of Rac1 or Cdc42 mutant...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2682539/ https://ncbi.nlm.nih.gov/pubmed/19443691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902501106 |
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