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The small G-proteins Rac1 and Cdc42 are essential for myoblast fusion in the mouse

Rac1 and Cdc42 are small G-proteins that regulate actin dynamics and affect plasma membrane protrusion and vesicle traffic. We used conditional mutagenesis in mice to demonstrate that Rac1 and Cdc42 are essential for myoblast fusion in vivo and in vitro. The deficit in fusion of Rac1 or Cdc42 mutant...

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Bibliografische gegevens
Hoofdauteurs: Vasyutina, Elena, Martarelli, Benedetta, Brakebusch, Cord, Wende, Hagen, Birchmeier, Carmen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682539/
https://ncbi.nlm.nih.gov/pubmed/19443691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902501106
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