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Nuclear movement during myotube formation is microtubule and dynein dependent and is regulated by Cdc42, Par6 and Par3

Cells actively position their nucleus within the cytoplasm. One striking example is observed during skeletal myogenesis. Differentiated myoblasts fuse to form a multinucleated myotube with nuclei positioned in the centre of the syncytium by an unknown mechanism. Here, we describe that the nucleus of...

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Detalhes bibliográficos
Main Authors: Cadot, Bruno, Gache, Vincent, Vasyutina, Elena, Falcone, Sestina, Birchmeier, Carmen, Gomes, Edgar R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410389/
https://ncbi.nlm.nih.gov/pubmed/22732842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.89
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