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Nuclear movement during myotube formation is microtubule and dynein dependent and is regulated by Cdc42, Par6 and Par3

Cells actively position their nucleus within the cytoplasm. One striking example is observed during skeletal myogenesis. Differentiated myoblasts fuse to form a multinucleated myotube with nuclei positioned in the centre of the syncytium by an unknown mechanism. Here, we describe that the nucleus of...

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Autors principals: Cadot, Bruno, Gache, Vincent, Vasyutina, Elena, Falcone, Sestina, Birchmeier, Carmen, Gomes, Edgar R
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410389/
https://ncbi.nlm.nih.gov/pubmed/22732842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.89
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