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Aggravation of acute kidney injury by mPGES-2 down regulation is associated with autophagy inhibition and enhanced apoptosis
The deletion of microsomal prostaglandin E synthase-2 (mPGES-2) does not affect in vivo PGE(2) production, and the function of this enzyme remains unknown until now. This study investigated the expression and roles of mPGES-2 in LPS induced acute kidney injury (AKI) both in vitro and in vivo. We fou...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5579259/ https://ncbi.nlm.nih.gov/pubmed/28860615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10271-8 |
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