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Presenilin1/γ-secretase protects neurons from glucose deprivation–induced death by regulating miR-212 and PEA15
Reduced cerebral glucose utilization is found in aged individuals and often is an early sign of neurodegeneration. Here, we show that under glucose deprivation (GD) conditions, decreased expression of presenilin 1 (PS1) results in decreased neuronal survival, whereas increased PS1 increases neuronal...
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| Veröffentlicht in: | FASEB J |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Federation of American Societies for Experimental Biology
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5731132/ https://ncbi.nlm.nih.gov/pubmed/28855274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700447RR |
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