Wird geladen...
Presenilin 1 is necessary for neuronal, but not glial, EGFR expression and neuroprotection via γ-secretase-independent transcriptional mechanisms
Epidermal growth factor receptor (EGFR) plays pivotal roles in cell proliferation, differentiation, and tissue development, while EGFs protect neurons from toxic insults by binding EGFR and stimulating survival signaling. Furthermore, recent evidence implicates this receptor in neurometabolic disord...
Gespeichert in:
Veröffentlicht in: | FASEB J |
---|---|
Hauptverfasser: | , , , , , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Federation of American Societies for Experimental Biology
2015
|
Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4550373/ https://ncbi.nlm.nih.gov/pubmed/25985800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-270645 |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|