Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals

Patient-derived HIV-1 subtype B Nef clones downregulate HLA-A more efficiently than HLA-B. However, it remains unknown whether this property is common to Nef proteins across primate lentiviruses and how antiviral immune responses may be affected. We examined 263 Nef clones from diverse primate lenti...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Virol
मुख्य लेखकों: Mwimanzi, Francis, Toyoda, Mako, Mahiti, Macdonald, Mann, Jaclyn K., Martin, Jeffrey N., Bangsberg, David, Brockman, Mark A., Goulder, Philip, Kirchhoff, Frank, Brumme, Zabrina L., Ndung'u, Thumbi, Ueno, Takamasa
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2017
विषय:
Pathogenesis and Immunity
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730772/
https://ncbi.nlm.nih.gov/pubmed/29046444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01409-17
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन