Modelling and in vitro testing of the HIV-1 Nef fitness landscape

An effective vaccine is urgently required to curb the HIV-1 epidemic. We have previously described an approach to model the fitness landscape of several HIV-1 proteins, and have validated the results against experimental and clinical data. The fitness landscape may be used to identify mutation patte...

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Detalhes bibliográficos
Publicado no:Virus Evol
Main Authors: Barton, John P, Rajkoomar, Erasha, Mann, Jaclyn K, Murakowski, Dariusz K, Toyoda, Mako, Mahiti, Macdonald, Mwimanzi, Phillip, Ueno, Takamasa, Chakraborty, Arup K, Ndung’u, Thumbi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680064/
https://ncbi.nlm.nih.gov/pubmed/31392033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ve/vez029
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