TLR5 signaling in murine bone marrow induces hematopoietic progenitor cell proliferation and aids survival from radiation

Administration of the bacterial protein flagellin to mice activates innate immune signaling that protects against an array of challenges, including ionizing radiation. Herein, we define the underlying mechanism for this protection. We report that flagellin treatment induces proliferation and mobiliz...

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Bibliografiske detaljer
Udgivet i:Blood Adv
Main Authors: Zhang, Benyue, Oyewole-Said, Damilola, Zou, Jun, Willliams, Ifor R., Gewirtz, Andrew T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2017
Fag:
Hematopoiesis and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728097/
https://ncbi.nlm.nih.gov/pubmed/29296826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017006981
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