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TLR5 signaling in murine bone marrow induces hematopoietic progenitor cell proliferation and aids survival from radiation

Administration of the bacterial protein flagellin to mice activates innate immune signaling that protects against an array of challenges, including ionizing radiation. Herein, we define the underlying mechanism for this protection. We report that flagellin treatment induces proliferation and mobiliz...

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Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Zhang, Benyue, Oyewole-Said, Damilola, Zou, Jun, Willliams, Ifor R., Gewirtz, Andrew T.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728097/
https://ncbi.nlm.nih.gov/pubmed/29296826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017006981
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