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PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cells
Protein kinase R (PKR) is an interferon (IFN)-inducible, double-stranded RNA-activated kinase that initiates apoptosis in response to cellular stress. To determine the role of PKR in hematopoiesis, we developed transgenic mouse models that express either human PKR (TgPKR) or a dominant-negative PKR...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Hematology
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3637012/ https://ncbi.nlm.nih.gov/pubmed/23403623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-09-456400 |
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