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TLR5 signaling in murine bone marrow induces hematopoietic progenitor cell proliferation and aids survival from radiation

Administration of the bacterial protein flagellin to mice activates innate immune signaling that protects against an array of challenges, including ionizing radiation. Herein, we define the underlying mechanism for this protection. We report that flagellin treatment induces proliferation and mobiliz...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Zhang, Benyue, Oyewole-Said, Damilola, Zou, Jun, Willliams, Ifor R., Gewirtz, Andrew T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728097/
https://ncbi.nlm.nih.gov/pubmed/29296826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017006981
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