TLR5 signaling in murine bone marrow induces hematopoietic progenitor cell proliferation and aids survival from radiation

Administration of the bacterial protein flagellin to mice activates innate immune signaling that protects against an array of challenges, including ionizing radiation. Herein, we define the underlying mechanism for this protection. We report that flagellin treatment induces proliferation and mobiliz...

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Vydáno v:Blood Adv
Hlavní autoři: Zhang, Benyue, Oyewole-Said, Damilola, Zou, Jun, Willliams, Ifor R., Gewirtz, Andrew T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2017
Témata:
Hematopoiesis and Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728097/
https://ncbi.nlm.nih.gov/pubmed/29296826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017006981
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