Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing

Characterising the hierarchy of mammary epithelial cells (MECs) and how they are regulated during adult development is important for understanding how breast cancer arises. Here we report the use of single-cell RNA sequencing to determine the gene expression profile of MECs across four developmental...

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Udgivet i:Nat Commun
Main Authors: Bach, Karsten, Pensa, Sara, Grzelak, Marta, Hadfield, James, Adams, David J., Marioni, John C., Khaled, Walid T.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723634/
https://ncbi.nlm.nih.gov/pubmed/29225342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02001-5
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