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Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing

Characterising the hierarchy of mammary epithelial cells (MECs) and how they are regulated during adult development is important for understanding how breast cancer arises. Here we report the use of single-cell RNA sequencing to determine the gene expression profile of MECs across four developmental...

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Pubblicato in:Nat Commun
Autori principali: Bach, Karsten, Pensa, Sara, Grzelak, Marta, Hadfield, James, Adams, David J., Marioni, John C., Khaled, Walid T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723634/
https://ncbi.nlm.nih.gov/pubmed/29225342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02001-5
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