Separation and Characterization of Epithelial and Mesenchymal-like Murine Mammary Tumor Cells Reveals Epithelial Cell Differentiation Plasticity and Enhanced Tumorigenicity of Epithelial-enriched Tumor Cells

Tumors are composed of heterogeneous populations of cells including tumor-initiating cells (TICs) and metastatic precursors. While the origin of these cells is unknown, there is evidence that tumor cells can transdifferentiate from an epithelial to a mesenchymal phenotype, a property referred to as...

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Detalhes bibliográficos
Main Authors: Palen, Katie A., Jing, Weiqing, Weber, James J., Tilkens, Sara B., Chan, Andrew M., Johnson, Bryon D., Gershan, Jill A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601216/
https://ncbi.nlm.nih.gov/pubmed/22237886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12307-011-0095-2
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