Novel dynamics of human mucociliary differentiation revealed by single-cell RNA sequencing of nasal epithelial cultures

The upper airway epithelium, which is mainly composed of multiciliated, goblet, club and basal cells, ensures proper mucociliary function and can regenerate in response to assaults. In chronic airway diseases, defective repair leads to tissue remodeling. Delineating key drivers of differentiation dy...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Ruiz García, Sandra, Deprez, Marie, Lebrigand, Kevin, Cavard, Amélie, Paquet, Agnès, Arguel, Marie-Jeanne, Magnone, Virginie, Truchi, Marin, Caballero, Ignacio, Leroy, Sylvie, Marquette, Charles-Hugo, Marcet, Brice, Barbry, Pascal, Zaragosi, Laure-Emmanuelle
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Techniques and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826037/
https://ncbi.nlm.nih.gov/pubmed/31558434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.177428
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