Loading...

Hybrid Structure of the RagA/C-Ragulator mTORC1 Activation Complex

The lysosomal membrane is the locus for sensing cellular nutrient levels, which are transduced to mTORC1 via the Rag GTPases and the Ragulator complex. The crystal structure of the five-subunit human Ragulator at 1.4 Å resolution was determined. Lamtor1 wraps around the other four subunits to stabil...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Su, Ming-Yuan, Morris, Kyle L., Kim, Do Jin, Fu, Yangxue, Lawrence, Rosalie, Stjepanovic, Goran, Zoncu, Roberto, Hurley, James H.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722659/
https://ncbi.nlm.nih.gov/pubmed/29107538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.10.016
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!