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Functional analysis of a CDKN2A 5’UTR germline variant associated with pancreatic cancer development

CDKN2A coding region germline variants are associated with pancreatic adenocarcinoma (PC) susceptibility. Recently, we described functional germline 5’UTR CDKN2A variants from melanoma patients affecting the post-transcriptional regulation of p16(INK4a) mRNA that is dependent, at least in part, on a...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Bruno, William, Andreotti, Virginia, Bisio, Alessandra, Pastorino, Lorenza, Fornarini, Giuseppe, Sciallero, Stefania, Bianchi-Scarrà, Giovanna, Inga, Alberto, Ghiorzo, Paola
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720692/
https://ncbi.nlm.nih.gov/pubmed/29216274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189123
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