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Multiple rare variants in high-risk pancreatic cancer related genes may increase risk for pancreatic cancer in a subset of patients with and without germline CDKN2A mutations
The risk of pancreatic cancer (PC) is increased in melanoma-prone families but the causal relationship between germline CDKN2A mutations and PC risk is uncertain, suggesting the existence of non-CDKN2A factors. One genetic possibility involves patients having mutations in multiple high-risk PC-relat...
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| Izdano u: | Hum Genet |
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| Glavni autori: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5152573/ https://ncbi.nlm.nih.gov/pubmed/27449771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-016-1715-1 |
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