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Functional analysis of a CDKN2A 5’UTR germline variant associated with pancreatic cancer development
CDKN2A coding region germline variants are associated with pancreatic adenocarcinoma (PC) susceptibility. Recently, we described functional germline 5’UTR CDKN2A variants from melanoma patients affecting the post-transcriptional regulation of p16(INK4a) mRNA that is dependent, at least in part, on a...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5720692/ https://ncbi.nlm.nih.gov/pubmed/29216274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189123 |
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