Universal Patterns of Selection in Cancer and Somatic Tissues

Cancer develops as a result of somatic mutation and clonal selection, but quantitative measures of selection in cancer evolution are lacking. We adapted methods from molecular evolution and applied them to 7,664 tumors across 29 cancer types. Unlike species evolution, positive selection outweighs ne...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell
Egile Nagusiak: Martincorena, Iñigo, Raine, Keiran M., Gerstung, Moritz, Dawson, Kevin J., Haase, Kerstin, Van Loo, Peter, Davies, Helen, Stratton, Michael R., Campbell, Peter J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720395/
https://ncbi.nlm.nih.gov/pubmed/29056346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.09.042
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