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Universal Patterns of Selection in Cancer and Somatic Tissues
Cancer develops as a result of somatic mutation and clonal selection, but quantitative measures of selection in cancer evolution are lacking. We adapted methods from molecular evolution and applied them to 7,664 tumors across 29 cancer types. Unlike species evolution, positive selection outweighs ne...
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| Publicado en: | Cell |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cell Press
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5720395/ https://ncbi.nlm.nih.gov/pubmed/29056346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.09.042 |
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