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Somatic mutation and clonal expansions in human tissues

Recent sequencing studies on healthy skin and esophagus have found that, as we age, these tissues become colonized by mutant clones of cells carrying driver mutations in traditional cancer genes. This comment summarizes these findings and discusses their possible implications for our understanding o...

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Detalhes bibliográficos
Publicado no:Genome Med
Autor principal: Martincorena, Inigo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537184/
https://ncbi.nlm.nih.gov/pubmed/31138277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0648-4
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