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Somatic mutation and clonal expansions in human tissues

Recent sequencing studies on healthy skin and esophagus have found that, as we age, these tissues become colonized by mutant clones of cells carrying driver mutations in traditional cancer genes. This comment summarizes these findings and discusses their possible implications for our understanding o...

詳細記述

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書誌詳細
出版年:Genome Med
第一著者: Martincorena, Inigo
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537184/
https://ncbi.nlm.nih.gov/pubmed/31138277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0648-4
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