High-Definition Mapping of Four Spatially Distinct Neutralizing Epitope Clusters on RiVax, a Candidate Ricin Toxin Subunit Vaccine

RiVax is a promising recombinant ricin toxin A subunit (RTA) vaccine antigen that has been shown to be safe and immunogenic in humans and effective at protecting rhesus macaques against lethal-dose aerosolized toxin exposure. We previously used a panel of RTA-specific monoclonal antibodies (MAbs) to...

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Detalhes bibliográficos
Publicado no:Clin Vaccine Immunol
Main Authors: Toth, Ronald T., Angalakurthi, Siva Krishna, Van Slyke, Greta, Vance, David J., Hickey, John M., Joshi, Sangeeta B., Middaugh, C. Russell, Volkin, David B., Weis, David D., Mantis, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5717194/
https://ncbi.nlm.nih.gov/pubmed/29046307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00237-17
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