Fine-Specificity Epitope Analysis Identifies Contact Points on Ricin Toxin Recognized by Protective Monoclonal Antibodies

Ricin is a fast-acting protein toxin classified by the Centers for Disease Control and Prevention as a biothreat agent. In this report, we describe five new mouse mAbs directed against an immunodominant region, so-called epitope cluster II, on the surface of ricin’s ribosome-inactivating enzymatic s...

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Bibliografiska uppgifter
I publikationen:Immunohorizons
Huvudupphovsmän: Van Slyke, Greta, Angalakurthi, Siva Krishna, Toth, Ronald T., Vance, David J., Rong, Yinghui, Ehrbar, Dylan, Shi, Yuqi, Middaugh, C Russell, Volkin, David B., Weis, David D., Mantis, Nicholas J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372112/
https://ncbi.nlm.nih.gov/pubmed/30766971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/immunohorizons.1800042
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