High-Resolution Epitope Positioning of a Large Collection of Neutralizing and Nonneutralizing Single-Domain Antibodies on the Enzymatic and Binding Subunits of Ricin Toxin

We previously produced a heavy-chain-only antibody (Ab) VH domain (V(H)H)-displayed phage library from two alpacas that had been immunized with ricin toxoid and nontoxic mixtures of the enzymatic ricin toxin A subunit (RTA) and binding ricin toxin B subunit (RTB) (D. J. Vance, J. M. Tremblay, N. J....

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Detalles Bibliográficos
Publicado en:Clin Vaccine Immunol
Main Authors: Vance, David J., Tremblay, Jacqueline M., Rong, Yinghui, Angalakurthi, Siva Krishna, Volkin, David B., Middaugh, C. Russell, Weis, David D., Shoemaker, Charles B., Mantis, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
Assuntos:
Clinical Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5717184/
https://ncbi.nlm.nih.gov/pubmed/29021300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00236-17
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