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RiVax, a recombinant ricin subunit vaccine, protects mice against ricin delivered by gavage or aerosol
Ricin is a plant toxin that is a CDC level B biothreat. Our recombinant ricin A chain vaccine (RiVax), which contains mutations in both known toxic sites, has no residual toxicity at doses at least 800 times the immunogenic dose. RiVax without adjuvant given intramuscularly (i.m.) protected mice aga...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2049008/ https://ncbi.nlm.nih.gov/pubmed/17875350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.08.018 |
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