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Pilot Phase IB Clinical Trial of an Alhydrogel-Adsorbed Recombinant Ricin Vaccine

There is no FDA-approved vaccine for the potent plant toxin ricin. We have developed a recombinant ricin vaccine, RiVax. Without adjuvant it is safe and immunogenic in mice, rabbits, and humans. Based on our studies in mice, we now report the results of a small clinical trial with Alhydrogel-adsorbe...

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Detalhes bibliográficos
Main Authors: Vitetta, Ellen S., Smallshaw, Joan E., Schindler, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485895/
https://ncbi.nlm.nih.gov/pubmed/22914366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00381-12
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