Structure of RiVax: a recombinant ricin vaccine

RiVax is a recombinant protein that is currently under clinical development as part of a human vaccine to protect against ricin poisoning. RiVax includes ricin A-chain (RTA) residues 1–267 with two intentional amino-acid substitutions, V76M and Y80A, aimed at reducing toxicity. Here, the crystal str...

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Bibliographic Details
Main Authors: Legler, Patricia M., Brey, Robert N., Smallshaw, Joan E., Vitetta, Ellen S., Millard, Charles B.
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2011
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169317/
https://ncbi.nlm.nih.gov/pubmed/21904036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444911026771
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