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RiVax, a recombinant ricin subunit vaccine, protects mice against ricin delivered by gavage or aerosol

Ricin is a plant toxin that is a CDC level B biothreat. Our recombinant ricin A chain vaccine (RiVax), which contains mutations in both known toxic sites, has no residual toxicity at doses at least 800 times the immunogenic dose. RiVax without adjuvant given intramuscularly (i.m.) protected mice aga...

詳細記述

保存先:
書誌詳細
主要な著者: Smallshaw, Joan E., Richardson, James A., Vitetta, Ellen S.
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2049008/
https://ncbi.nlm.nih.gov/pubmed/17875350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.08.018
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