A common mechanism for CFTR potentiators

Cystic fibrosis (CF) is a channelopathy caused by loss-of-function mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which encodes a phosphorylation-activated and adenosine triphosphate (ATP)–gated chloride channel. In the past few years, high-throughput drug screenin...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Gen Physiol
Main Authors: Yeh, Han-I, Sohma, Yoshiro, Conrath, Katja, Hwang, Tzyh-Chang
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2017
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715911/
https://ncbi.nlm.nih.gov/pubmed/29079713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201711886
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