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Nonintegral stoichiometry in CFTR gating revealed by a pore-lining mutation
Cystic fibrosis transmembrane conductance regulator (CFTR) is a unique member of the ATP-binding cassette (ABC) protein superfamily. Unlike most other ABC proteins that function as active transporters, CFTR is an ATP-gated chloride channel. The opening of CFTR’s gate is associated with ATP-induced d...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3457689/ https://ncbi.nlm.nih.gov/pubmed/22966014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210834 |
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