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CFTR potentiators: From Bench to Bedside

One major breakthrough in cystic fibrosis research in the past decade is the development of drugs that target the root cause of the disease—dysfunctional CFTR protein. One of the compounds, Ivacaftor or Kalydeco, which has been approved for clinical use since 2012, acts by promoting the gating funct...

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Detalhes bibliográficos
Publicado no:Curr Opin Pharmacol
Main Authors: Jih, Kang-Yang, Lin, Wen-Ying, Sohma, Yoshiro, Hwang, Tzyh-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723237/
https://ncbi.nlm.nih.gov/pubmed/29073476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2017.09.015
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