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State-dependent modulation of CFTR gating by pyrophosphate

Cystic fibrosis transmembrane conductance regulator (CFTR) is an adenosine triphosphate (ATP)-gated chloride channel. ATP-induced dimerization of CFTR's two nucleotide-binding domains (NBDs) has been shown to reflect the channel open state, whereas hydrolysis of ATP is associated with channel c...

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Sonraí Bibleagrafaíochta
Main Authors: Tsai, Ming-Feng, Shimizu, Hiroyasu, Sohma, Yoshiro, Li, Min, Hwang, Tzyh-Chang
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699106/
https://ncbi.nlm.nih.gov/pubmed/19332621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810186
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