A stable ATP binding to the nucleotide binding domain is important for reliable gating cycle in an ABC transporter CFTR

Cystic fibrosis transmembrane conductance regulator (CFTR) anion channel, a member of ABC transporter superfamily, gates following ATP-dependent conformational changes of the nucleotide binding domains (NBD). Reflecting the hundreds of milliseconds duration of the channel open state corresponding to...

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Vydáno v:J Physiol Sci
Hlavní autoři: Shimizu, Hiroyasu, Yu, Ying-Chun, Kono, Koichi, Kubota, Takahiro, Yasui, Masato, Li, Min, Hwang, Tzyh-Chang, Sohma, Yoshiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Japan 2010
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939245/
https://ncbi.nlm.nih.gov/pubmed/20628841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12576-010-0102-2
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