High affinity ATP/ADP analogues as new tools for studying CFTR gating

Previous studies using non-hydrolysable ATP analogues and hydrolysis-deficient cystic fibrosis transmembrane conductance regulator (CFTR) mutants have indicated that ATP hydrolysis precedes channel closing. Our recent data suggest that ATP binding is also important in modulating the closing rate. Th...

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Detalhes bibliográficos
Main Authors: Zhou, Zhen, Wang, Xiaohui, Li, Min, Sohma, Yoshiro, Zou, Xiaoqin, Hwang, Tzyh-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Molecular and Genomic Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464241/
https://ncbi.nlm.nih.gov/pubmed/16223764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.095083
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