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CFTR Gating II: Effects of Nucleotide Binding on the Stability of Open States
Previously, we demonstrated that ADP inhibits cystic fibrosis transmembrane conductance regulator (CFTR) opening by competing with ATP for a binding site presumably in the COOH-terminal nucleotide binding domain (NBD2). We also found that the open time of the channel is shortened in the presence of...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1289160/ https://ncbi.nlm.nih.gov/pubmed/15767296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200409228 |
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