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Nonequilibrium Gating of CFTR on an Equilibrium Theme
Malfunction of cystic fibrosis transmembrane conductance regulator (CFTR), a member of the ABC protein superfamily that functions as an ATP-gated chloride channel, causes the lethal genetic disease, cystic fibrosis. This review focuses on the most recent findings on the gating mechanism of CFTR. Pot...
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| Pubblicato in: | Physiology (Bethesda) |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4931552/ https://ncbi.nlm.nih.gov/pubmed/23223629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiol.00026.2012 |
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