EZH2 modifies sunitinib resistance in renal cell carcinoma by kinome reprogramming

Acquired and intrinsic resistance to receptor tyrosine kinase inhibitors (RTKi) represent a major hurdle in improving the management of clear cell renal cell carcinoma (ccRCC). Recent reports suggest that drug resistance is driven by tumor adaptation via epigenetic mechanisms that activate alternati...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cancer Res
Κύριοι συγγραφείς: Adelaiye-Ogala, Remi, Budka, Justin, Damayanti, Nur P., Arrington, Justine, Ferris, Mary, Hsu, Chuan-Chih, Chintala, Sreenivasulu, Orillion, Ashley, Miles, Kiersten Marie, Shen, Li, Elbanna, May, Ciamporcero, Eric, Arisa, Sreevani, Pettazzoni, Piergiorgio, Draetta, Giulio F., Seshadri, Mukund, Hancock, Bradley, Radovich, Milan, Kota, Janaiah, Buck, Michael, Keilhack, Heike, McCarthy, Brian P., Persohn, Scott A., Territo, Paul R., Zang, Yong, Irudayaraj, Joseph, Tao, W. Andy, Hollenhorst, Peter, Pili, Roberto
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2017
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712262/
https://ncbi.nlm.nih.gov/pubmed/28978636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0899
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