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A small cassette enables conditional gene inactivation by CRISPR/Cas9
The availability of CRISPR/Cas9 technology has enabled the rapid establishment of gene knockouts in many cell types and even whole organisms. However, conditional inactivation of essential genes remains a challenge. We devised an approach named DECAI (DEgradation based on Cre-regulated- Artificial I...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5711947/ https://ncbi.nlm.nih.gov/pubmed/29196747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16931-z |
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