Inactivation of Cancer Mutations Utilizing CRISPR/Cas9

Although whole-genome sequencing has uncovered a large number of mutations that drive tumorigenesis, functional ratification for most mutations remains sparse. Here, we present an approach to test functional relevance of tumor mutations employing CRISPR/Cas9. Combining comprehensive sgRNA design and...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Natl Cancer Inst
Main Authors: Gebler, Christina, Lohoff, Tim, Paszkowski-Rogacz, Maciej, Mircetic, Jovan, Chakraborty, Debojyoti, Camgoz, Aylin, Hamann, Martin V, Theis, Mirko, Thiede, Christian, Buchholz, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284257/
https://ncbi.nlm.nih.gov/pubmed/27576906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djw183
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados