Llwytho...
Reprogramming MHC specificity by CRISPR-Cas9-assisted cassette exchange
The development of programmable nucleases has enabled the application of new genome engineering strategies for cellular immunotherapy. While targeted nucleases have mostly been used to knock-out or knock-in genes in immune cells, the scarless exchange of entire immunogenomic alleles would be of grea...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Sci Rep |
|---|---|
| Prif Awduron: | , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Nature Publishing Group
2017
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5379551/ https://ncbi.nlm.nih.gov/pubmed/28374766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45775 |
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