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Protonation Enhances the Inherent Helix-Forming Propensity of pHLIP
[Image: see text] Cell-penetrating peptides (CPPs) can be potentially used in targeted delivery of therapeutic cargoes. However, their conformation in solution is poorly understood. We employed molecular dynamics simulations to probe the structural fluctuations of an anionic CPP, pH Low Insertion Pe...
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| Publicado no: | ACS Omega |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2017
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5709774/ https://ncbi.nlm.nih.gov/pubmed/29214239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01371 |
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