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Cooperative Nonbonded Forces Control Membrane Binding of the pH-Low Insertion Peptide pHLIP

Peptides with the ability to bind and insert into the cell membrane have immense potential in biomedical applications. pH (low) insertion peptide (pHLIP), a water-soluble polypeptide derived from helix C of bacteriorhodopsin, can insert into a membrane at acidic pH to form a stable transmembrane α-h...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Gupta, Chitrak, Ren, Yue, Mertz, Blake
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301916/
https://ncbi.nlm.nih.gov/pubmed/30503536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.11.002
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