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Bilayer Thickness and Curvature Influence Binding and Insertion of a pHLIP Peptide

The physical properties of lipid bilayers, such as curvature and fluidity, can affect the interactions of polypeptides with membranes, influencing biological events. Additionally, given the growing interest in peptide-based therapeutics, understanding the influence of membrane properties on membrane...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Karabadzhak, Alexander G., Weerakkody, Dhammika, Deacon, John, Andreev, Oleg A., Reshetnyak, Yana K., Engelman, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961746/
https://ncbi.nlm.nih.gov/pubmed/29742404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.03.036
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