Modulation of the pHLIP Transmembrane Helix Insertion Pathway

The membrane-associated folding/unfolding of pH (low) insertion peptide (pHLIP) provides an opportunity to study how sequence variations influence the kinetics and pathway of peptide insertion into bilayers. Here, we present the results of steady-state and kinetics investigations of several pHLIP va...

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Autors principals: Karabadzhak, Alexander G., Weerakkody, Dhammika, Wijesinghe, Dayanjali, Thakur, Mak S., Engelman, Donald M., Andreev, Oleg A., Markin, Vladislav S., Reshetnyak, Yana K.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2012
Matèries:
Membrane
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328699/
https://ncbi.nlm.nih.gov/pubmed/22768940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.021
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