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pH (low) insertion peptide (pHLIP) inserts across a lipid bilayer as a helix and exits by a different path
What are the molecular events that occur when a peptide inserts across a membrane or exits from it? Using the pH-triggered insertion of the pH low insertion peptide to enable kinetic analysis, we show that insertion occurs in several steps, with rapid (0.1 sec) interfacial helix formation, followed...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840156/ https://ncbi.nlm.nih.gov/pubmed/20160113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914330107 |
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